Immune Response and Hypersensitivity

Axia College Material Appendix C Immune Response and Hypersensitivity pierce tease Multimedia Activity After completing the Puncture Wound Multimedia Activity, complete the table below. List the four events of the inflammatory repartee covered in the activity in the order of occurrence. Rewrite the events in your own words, using vocabulary terms from Ch. 2 of the text. Vascular Events in an Inflammatory Response Events Simplified commentary of event Professional description of event 1st Germs from the discover argon introduced below the skin. The skin is disjointed in some way, in this case by a nail puncturing the skin. When this occurs, it allows the entry of pathogens (germs such as bacteria) into the wound. 2nd Surrounding cells leak legato that affects the affinity An immediate local innate response in the give tissues vessels. is generated by components of the insubordinate system which are present in those tissues.Those components of the immune syst em include macrophages (a type of white blood cell) and balance proteins (proteins that are involved in the initial immune response). 3rd The fluid bear upon the surrounding blood vessels causes Other immune cells (such as neutrophils), leave the the set down of other cells into the tissue. circulation, attracted by the inflammatory mediators released by the mast cells and enter the wounded area. quaternary As the wounded part of the body reacts to the germs, The neutrophil cells attack the pathogens that deal entered certain cells destroy these germs. the wound and begin to kill them.In the meantime, another narrow immune cell, known as the dendrite cell, carried parts of the dead pathogen back to the nigh lymphatic system. Hypersensitivity Give a brief description and example in your own words for each of the four types of hypersensitivity presented in Ch. 2. Hypersensitivity Matrix typesetters case of Hypersensitivity Description Example Type I Alle rgic/Anaphylactic Anaphylaxisis an subtleAnaphylaxis is often triggered by substances that are injected or ingested and multi-system severe thereby watch access into the blood stream. An explosive reaction involving the skin, type I hypersensitivitylungs, nose, throat, and gastrointestinal tract can then result. reaction. Type II Cytotoxic/cytolytic Cytotoxic are caused byThe reaction of the antibody attachment leads to the activation of complement antibodies, which proteins (again, encountered earlier). The complement proteins destroy the persons attach to a persons own blood cells.Type II reactions often occur in incompatible blood transfusions. own blood cells or tissue cells. Type III Immune Complex Animmune complexis After anantigen-antibody reaction, the immune complexes can be subject to all of a formed from the number of responses, includingcomplementdeposition,opsonization,phagocytosis, or integral top of an processing byproteases. antibody to a sol uble antigen. Type IV Cell-mediated/ slowType IV (cell-mediated)Cell-mediated immunity is directed primarily at microbes that win reactions appear 12-72 inphagocytesandmicrobesthat infect non-phagocytic cells. hours after exposure to an allergen.